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Cheryl Guttman Krader
Weighing IOP fluctuation in glaucoma progression
Available evidence indicates that long-term IOP fluctuation is an important factor in glaucoma progression, said Joseph Caprioli, MD. Based on this information he encouraged ophthalmologists to consider IOP “modulation” rather than “reduction.”
Looking to long-range keratoprosthesis outcomes
Findings from a single-surgeon consecutive series including 97 eyes with up to 12 years of follow-up provide realistic insights for corneal surgeons about long-term outcomes after implantation of the Boston keratoprosthesis type 1 (“Boston KPro”; Massachusetts Eye and Ear Infirmary). The information—which included analyses of visual acuity results, device retention rates, and complications associated with the permanent keratoprosthesis—was presented by Anthony J. Aldave, MD, at Cornea 2016.
How the cornea contributes to IOL power calculation
Under the best of circumstances—meaning when cataract surgery is performed in an eye with a normal cornea by expert hands and with use of an advanced IOL power calculation formula—the achieved refractive outcome will be more than 0.5 D off target in 1 out of every 11 eyes.
Examining NSAID prevention of pseudophakic CME
Adding a topical nonsteroidal anti-inflammatory drug (NSAID) to treatment with a topical corticosteroid significantly reduces the incidence of clinical pseudophakic cystoid macular edema (PCME) in at-risk eyes.
Targeting refractory vitreous seeds in retinoblastoma
A retrospective study reviewing outcomes of 17 consecutive eyes with retinoblastoma treated for refractory vitreous seeds found intravitreal topotecan was safe and resulted in complete regression in all eyes after a mean of three injections.
Exploring anti-VEGF therapy for orbital vascular lesions
Findings from immunohistochemical analysis of vascular endothelial growth factor (VEGF) receptor expression on pathology specimens of orbital vascular tumors suggest a potential therapeutic role for anti-VEGF agents.
Silicone oil complications mostly manageable
Complications of silicone oil occur when it is inadvertently placed in anatomic areas other than the vitreous cavity, migrates, or emulsifies. Methods for avoiding these issues and their management are discussed in this article.
Considering body posture after macular hole surgery
Retina surgeons discuss the need for face-down positioning after macular hole surgery. The interpretation of what constitutes “face-down” is key to their messages.
Exploring oral dual anti-VEGF/PDGF inhibitor for AMD
An oral anti-VEGF/PDGF inhibitor had no dose-limiting toxicity and improved visual acuity and OCT findings in patients with exudative age-related macular degeneration in a phase I study.
Achieving patient satisfaction with multifocal IOLs
Multifocal IOLs offer the potential to reduce spectacle dependence, but outcomes vary depending on optical design. Optimizing success and satisfaction depends on careful patient selection, thorough counseling, and good surgical technique.