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    6 things you need to know: Genetic markers for glaucoma identified


    How Vitamin D affects AMD

    A study published in Marturitas found that Vitamin D may help prevent age-related macular degeneration (AMD).

    According to the authors, Vitamin D may be involved in ocular function in older adults, but there is no current consensus on a possible association between circulating concentrations of 25-hydroxyvitamin D (25OHD) and the occurrence of AMD.

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    Researchers conducted a Medline search in November 2015, with no date limit, using the terms:

    • Vitamin D

    • Vitamin D deficiency

    • Ergocalciferols

    • Cholecalciferol combined with age-related macular degeneration

    • Macular degeneration

    • Retinal degeneration

    • Macula lutea

    • Retina

    Researchers say fixed and random-effects meta-analyses were performed to compute standard mean difference in 25OHD concentration between AMD and non-AMD patients and to identify the AMD risk according to circulating 25OHD concentration. Of the 243 retrieved studies, 11 observational studies—10 cross-sectional studies and one cohort study—met the selection criteria.

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    The study found that circulating 25OHD concentration was 15 percent lower in AMD compared with non-AMD on average. AMD was inversely associated with the highest 25OHD quintile compared with the, notably late AMD.

    Researchers concluded that high 25OHD concentrations may be protective against AMD.

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    Colleen E. McCarthy
    Colleen McCarthy is a freelance writer based in the Cleveland area and a former editor of Optometry Times. She is a 2010 graduate of the ...


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