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    Epicutaneous immunotherapy may transform allergy treatment

    Evolving EPIT procedures may help treatment options within optometry


    EPIT was shown to be successful in 1921 by by placing the allergen onto scarified skin, resulting in decreased allergy symptoms in patients allergic to horses. A rebirth began when French company DBV-Technologies went back to the engineering table to facilitate a novel process called “electrospray” to deliver a thin layer of specific proteins via intact skin on a patch.14 Currently, the FDA has given DBV’s product Viaskin a fast-track designation for peanuts and milk.15,16

    Related: An allergist talks allergy

    How EPIT works

    EPIT is similar to SLIT in that the allergen is delivered initially to a non-vascularized tissue, but it differs by decreasing the allergen-specific Th2 response with a sharper decrease of IL-4, IL-5, IL-10, and IL-13, a trend of increasing TGF-

    Michael S. Cooper, OD
    Michael S. Cooper, OD, is in private practice in Willimantic, CT. He is a consultant to Allergan, BioTissue, Johnson & Johnson Vision ...


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    Optometry Times A/V